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Molecular mechanisms of etoposide
Etoposide derives from podophyllotoxin, a toxin found in the American Mayapple. It was first synthesized in 1966 and approved for cancer therapy in 1983 by the U.S. Food and Drug Administration (Hande, 1998[25]). Starting from 1980s several studies demonstrated that etoposide targets DNA topoisomera...
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| Publicado no: | EXCLI J |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Leibniz Research Centre for Working Environment and Human Factors
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4652635/ https://ncbi.nlm.nih.gov/pubmed/26600742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2015-561 |
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