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Deep sea as a source of novel-anticancer drugs: update on discovery and preclinical/clinical evaluation in a systems medicine perspective

The deep-sea habitat is a source of very potent marine-derived agents that may inhibit the growth of human cancer cells “in vitro” and “in vivo”. Salinosporamide-A, Marizomib, by Salinispora species is a proteasome inhibitor with promising anticancer activity (Phase I/II trials). Different deep-sea-...

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Detalhes bibliográficos
Publicado no:EXCLI J
Main Authors: Russo, Patrizia, Del Bufalo, Alessandra, Fini, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: Leibniz Research Centre for Working Environment and Human Factors 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652633/
https://ncbi.nlm.nih.gov/pubmed/26600744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2014-632
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