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Reference-free inference of tumor phylogenies from single-cell sequencing data

BACKGROUND: Effective management and treatment of cancer continues to be complicated by the rapid evolution and resulting heterogeneity of tumors. Phylogenetic study of cell populations in single tumors provides a way to delineate intra-tumoral heterogeneity and identify robust features of evolution...

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Bibliografiske detaljer
Udgivet i:BMC Genomics
Main Authors: Subramanian, Ayshwarya, Schwartz, Russell
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652515/
https://ncbi.nlm.nih.gov/pubmed/26576947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-16-S11-S7
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