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The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes.

A translocation involving human chromosome 10, band q24, in a subset of T-cell acute leukemias disrupts a region surrounding the putative oncogene HOX11, which encodes a protein with a homeodomain. The HOX11 protein binds to a specific DNA sequence, it localizes to the cell nucleus, and it transacti...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Dear, T N, Sanchez-Garcia, I, Rabbitts, T H
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46525/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8099440/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.10.4431
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