Periodontal CD14 mRNA expression is downregulated in patients with chronic periodontitis and type 2 diabetes

BACKGROUND: Patients with type 2 diabetes mellitus (T2DM) have increased severity of periodontitis. Toll-like receptor (TLR)4, its co-receptors CD14 and MD-2, and adaptor MyD88 play pivotal roles in lipopolysaccharide (LPS)-triggered tissue inflammation and periodontitis. This study investigated the...

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Udgivet i:BMC Oral Health
Main Authors: Hedgpeth, Dustin C., Zhang, Xiaoming, Jin, Junfei, Leite, Renata S., Krayer, Joe W., Huang, Yan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652420/
https://ncbi.nlm.nih.gov/pubmed/26581717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12903-015-0118-3
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