Peritumoural neutrophils negatively regulate adaptive immunity via the PD-L1/PD-1 signalling pathway in hepatocellular carcinoma

BACKGROUND: PD-L1 expression on neutrophils contributes to the impaired immune response in infectious disease, but the detailed role of PD-L1 expression on neutrophils in HCC remains unclear. METHODS: We investigated the phenotype and morphology of neutrophils infiltrated in tumour tissues from both...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: He, Gaixia, Zhang, Henghui, Zhou, Jinxue, Wang, Beibei, Chen, Yanhui, Kong, Yaxian, Xie, Xingwang, Wang, Xueyan, Fei, Ran, Wei, Lai, Chen, Hongsong, Zeng, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652417/
https://ncbi.nlm.nih.gov/pubmed/26581194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0256-0
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