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Comparison of targeted next-generation sequencing and Sanger sequencing for the detection of PIK3CA mutations in breast cancer

BACKGROUND: Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha, PIK3CA, is one of the most frequently mutated genes in breast cancer, and the mutation status of PIK3CA has clinical relevance related to response to therapy. The aim of our study was to investigate the mutation sta...

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Detaylı Bibliyografya
Yayımlandı:BMC Clin Pathol
Asıl Yazarlar: Arsenic, Ruza, Treue, Denise, Lehmann, Annika, Hummel, Michael, Dietel, Manfred, Denkert, Carsten, Budczies, Jan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652376/
https://ncbi.nlm.nih.gov/pubmed/26587011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12907-015-0020-6
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