Improved Detection by Next-Generation Sequencing of Pyrazinamide Resistance in Mycobacterium tuberculosis Isolates

The technical limitations of common tests used for detecting pyrazinamide (PZA) resistance in Mycobacterium tuberculosis isolates pose challenges for comprehensive and accurate descriptions of drug resistance in patients with multidrug-resistant tuberculosis (MDR-TB). In this study, a 606-bp fragmen...

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發表在:J Clin Microbiol
Main Authors: Maningi, Nontuthuko E., Daum, Luke T., Rodriguez, John D., Mphahlele, Matsie, Peters, Remco P. H., Fischer, Gerald W., Chambers, James P., Fourie, P. Bernard
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2015
主題:
Mycobacteriology and Aerobic Actinomycetes
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652100/
https://ncbi.nlm.nih.gov/pubmed/26378284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01179-15
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