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Production of tumor necrosis factor and other proinflammatory cytokines by human mononuclear phagocytes stimulated with myelin P2 protein.

In this study we examined the effect of myelin P2 protein on some proinflammatory functions exerted by human mononuclear phagocytes. Northern blot analysis demonstrated that P2 protein selectively induced in monocytes and macrophages mRNA accumulation of tumor necrosis factor (TNF), interleukin 1 be...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Baron, P, Constantin, G, D'Andrea, A, Ponzin, D, Scarpini, E, Scarlato, G, Trinchieri, G, Rossi, F, Cassatella, M A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46521/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7685103/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.10.4414
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