Smooth Muscle CaMKIIδ Promotes Allergen Induced Airway Hyperresponsiveness and Inflammation

Airway smooth muscle (ASM) is a key target cell in allergen-induced asthma known to contribute to airway hyperresponsiveness (AHR) and chronic airway remodeling. Changes in ASM calcium homeostasis have been shown to contribute to AHR although the mechanisms and Ca(2+) signal effectors are incomplete...

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Pubblicato in:Pflugers Arch
Autori principali: Spinelli, Amy M., Liu, Yongfeng, Sun, Li-Yan, Gonzalez-Cobos, José C., Backs, Johannes, Trebak, Mohamed, Singer, Harold A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651734/
https://ncbi.nlm.nih.gov/pubmed/26089028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-015-1713-5
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