Kinetic Modeling and Constrained Reconstruction of Hyperpolarized [1-(13)C]-Pyruvate Offers Improved Metabolic Imaging of Tumors

Hyperpolarized [1-(13)C]-pyruvate has shown tremendous promise as an agent for imaging tumor metabolism with unprecedented sensitivity and specificity. Imaging hyperpolarized substrates by magnetic resonance is unlike traditional MRI because signals are highly transient and their spatial distributio...

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Publicado en:Cancer Res
Main Authors: Bankson, James A., Walker, Christopher M., Ramirez, Marc S., Stefan, Wolfgang, Fuentes, David, Merritt, Matthew E., Lee, Jaehyuk, Sandulache, Vlad C., Chen, Yunyun, Phan, Liem, Chou, Ping-Chieh, Rao, Arvind, Yeung, Sai-Ching J, Lee, Mong-Hong, Schellingerhout, Dawid, Conrad, Charles A., Malloy, Craig, Sherry, A. Dean, Lai, Stephen Y., Hazle, John D.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651725/
https://ncbi.nlm.nih.gov/pubmed/26420214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0171
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