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Aerosolized STAT1 Antisense Oligodeoxynucleotides Decrease the Concentrations of Inflammatory Mediators in Bronchoalveolar Lavage Fluid in Bleomycin-Induced Rat Pulmonary Fibrosis

It has been demonstrated that alveolar macrophages (AMs) play a key role in the pathogenesis of pulmonary fibrosis by releasing a variety of cytokines and inflammatory mediators. In addition, abnormal signal transducer and activator of transcription-1 (STAT1) activation in AMs may play a pivotal rol...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Zeng, Ming, Liao, Bin, Zhu, Chen, Wang, Wenjun, Zhan, Xiaoqin, Fan, Xianming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651273/
https://ncbi.nlm.nih.gov/pubmed/18582404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2008.27
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