Glutamate microinjection into the hypothalamic paraventricular nucleus attenuates ulcerative colitis in rats

AIM: To investigate the effects of glutamate microinjection into hypothalamic paraventricular nucleus (PVN) on ulcerative colitis (UC) in rats and to explore the relevant mechanisms. METHODS: 2,4,6-Trinitrobenzenesulfonic acid (100 mg/kg in 50% ethanol) was instilled into the colon of adult male SD...

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Bibliographic Details
Published in:Acta Pharmacol Sin
Main Authors: Li, Ting-ting, Zhang, Jian-fu, Fei, Su-juan, Zhu, Sheng-ping, Zhu, Jin-zhou, Qiao, Xiao, Liu, Zhang-bo
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2014
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651215/
https://ncbi.nlm.nih.gov/pubmed/24362327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.140
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