Reducing overdiagnosis by polygenic risk-stratified screening: findings from the Finnish section of the ERSPC

BACKGROUND: We derived estimates of overdiagnosis by polygenic risk groups and examined whether polygenic risk-stratified screening for prostate cancer reduces overdiagnosis. METHODS: We calculated the polygenic risk score based on genotypes of 66 known prostate cancer loci for 4967 men from the Fin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Pashayan, Nora, Pharoah, Paul DP, Schleutker, Johanna, Talala, Kirsi, Tammela, Teuvo LJ, Määttänen, Liisa, Harrington, Patricia, Tyrer, Jonathan, Eeles, Rosalind, Duffy, Stephen W, Auvinen, Anssi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Epidemiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651137/
https://ncbi.nlm.nih.gov/pubmed/26291059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.289
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados