Innate Antibacterial Activity in Female Genital Tract Secretions Is Associated with Increased Risk of HIV Acquisition

Greater inhibitory activity against Escherichia coli and levels of human β defensin (HBD)-2 in genital tract secretions predicted HIV acquisition in women in the HPTN 035 trial. We investigated whether higher levels of E. coli inhibitory activity and antimicrobial peptides in cervicovaginal lavage (...

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Bibliographic Details
Published in:AIDS Res Hum Retroviruses
Main Authors: Pellett Madan, Rebecca, Masson, Lindi, Tugetman, Jessica, Werner, Lise, Grobler, Anneke, Mlisana, Koleka, Lo, Yungtai, Che, Denise, Arnold, Kelly B., Karim, Salim S. Abdool, Passmore, Jo-Ann S., Herold, Betsy C.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2015
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651017/
https://ncbi.nlm.nih.gov/pubmed/26061218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2015.0011
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