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FXR expression is associated with dysregulated glucose and lipid levels in the offspring kidney induced by maternal obesity

BACKGROUND: Maternal obesity is associated with dysregulation of glucose and lipid metabolism with consequent exposure of the fetus to an abnormal metabolic milieu. It is recognized that maternal obesity predisposes offspring to chronic kidney disease (CKD). We aimed to determine whether the nuclear...

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Bibliografske podrobnosti
izdano v:Nutr Metab (Lond)
Main Authors: Glastras, Sarah J., Wong, Muh Geot, Chen, Hui, Zhang, Jie, Zaky, Amgad, Pollock, Carol A., Saad, Sonia
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650952/
https://ncbi.nlm.nih.gov/pubmed/26583035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12986-015-0032-3
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