Vaccination with Klebsiella pneumoniae-derived extracellular vesicles protects against bacteria-induced lethality via both humoral and cellular immunity

The emergence of multidrug-resistant Klebsiella pneumoniae highlights the need to develop preventive measures to ameliorate Klebsiella infections. Bacteria-derived extracellular vesicles (EVs) are spherical nanometer-sized proteolipids enriched with outer membrane proteins. Gram-negative bacteria-de...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Lee, Won-Hee, Choi, Hyun-Il, Hong, Sung-Wook, Kim, Kwang-sun, Gho, Yong Song, Jeon, Seong Gyu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650931/
https://ncbi.nlm.nih.gov/pubmed/26358222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2015.59
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