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Interleukin-27 ameliorates coxsackievirus-B3-induced viral myocarditis by inhibiting Th17 cells

BACKGROUND: Interleukin (IL)-27, which has both pro and anti- inflammatory properties, is a new discovered heterodimeric cytokine that belongs to IL-12 family. However, the expression pattern and functional role of IL-27 in viral myocarditis (VMC) has not been investigated. METHODS: BALB/c mice were...

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Dettagli Bibliografici
Pubblicato in:Virol J
Autori principali: Zhu, Hengshan, Lou, Chuang, Liu, Ping
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650905/
https://ncbi.nlm.nih.gov/pubmed/26578236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-015-0418-x
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