Sex differences in plasma clozapine and norclozapine concentrations in clinical practice and in relation to body mass index and plasma glucose concentrations: a retrospective survey

BACKGROUND: Clozapine is widely prescribed and, although effective, can cause weight gain and dysglycemia. The dysmetabolic effects of clozapine are thought to be more prevalent in women with this gender on average attaining 17 % higher plasma clozapine concentrations than men. METHODS: We investiga...

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Detalhes bibliográficos
Publicado no:Ann Gen Psychiatry
Main Authors: Anderson, Simon G., Livingston, Mark, Couchman, Lewis, Smith, Daniel J., Connolly, Moira, Miller, Joan, Flanagan, Robert J., Heald, A. H.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650861/
https://ncbi.nlm.nih.gov/pubmed/26583040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12991-015-0075-x
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