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Intracellular oxygen determined by respiration regulates localization of Ras and prenylated proteins

Reduction of mitochondrial DNA (mtDNA) content induces the reduction of oxidative phosphorylation and dependence on fermentative glycolysis, that is, the Warburg effect. In aggressive prostate cancer (PCa), the reduction of mtDNA reduces oxygen consumption, increases intracellular oxygen concentrati...

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Publicat a:Cell Death Dis
Autors principals: Kim, A, Davis, R, Higuchi, M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650746/
https://ncbi.nlm.nih.gov/pubmed/26181205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.64
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