Activation of the SIRT1/p66shc antiapoptosis pathway via carnosic acid-induced inhibition of miR-34a protects rats against nonalcoholic fatty liver disease

Recent studies have demonstrated that miR-34a expression is significantly upregulated and associated with apoptosis in nonalcoholic fatty liver disease (NAFLD). Carnosic acid (CA) is a novel antioxidant and a potential inhibitor of apoptosis in organ injury, including liver injury. This study aimed...

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Опубликовано в: :Cell Death Dis
Главные авторы: Shan, W, Gao, L, Zeng, W, Hu, Y, Wang, G, Li, M, Zhou, J, Ma, X, Tian, X, Yao, J
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650741/
https://ncbi.nlm.nih.gov/pubmed/26203862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.196
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