miR-205-5p-mediated downregulation of ErbB/HER receptors in breast cancer stem cells results in targeted therapy resistance

The ErbB tyrosine kinase receptor family has been shown to have an important role in tumorigenesis, and the expression of its receptor members is frequently deregulated in many types of solid tumors. Various drugs targeting these receptors have been approved for cancer treatment. Particularly, in br...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: De Cola, A, Volpe, S, Budani, M C, Ferracin, M, Lattanzio, R, Turdo, A, D'Agostino, D, Capone, E, Stassi, G, Todaro, M, Di Ilio, C, Sala, G, Piantelli, M, Negrini, M, Veronese, A, De Laurenzi, V
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650737/
https://ncbi.nlm.nih.gov/pubmed/26181203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.192
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