EV20, a Novel Anti-ErbB-3 Humanized Antibody, Promotes ErbB-3 Down-Regulation and Inhibits Tumor Growth In Vivo

ErbB-3 (HER-3) receptor is involved in tumor progression and resistance to therapy. Development of specific inhibitors impairing the activity of ErbB-3 is an attractive tool for cancer therapeutics. MP-RM-1, a murine monoclonal antibody targeting human ErbB-3, has shown anticancer activity in precli...

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Detalhes bibliográficos
Principais autores: Sala, Gianluca, Rapposelli, Ilario Giovanni, Ghasemi, Reza, Piccolo, Enza, Traini, Sara, Capone, Emily, Rossi, Cosmo, Pelliccia, Angela, Di Risio, Annalisa, D'Egidio, Maurizia, Tinari, Nicola, Muraro, Raffaella, Iacobelli, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890702/
https://ncbi.nlm.nih.gov/pubmed/24466370
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