miR-205-5p-mediated downregulation of ErbB/HER receptors in breast cancer stem cells results in targeted therapy resistance

The ErbB tyrosine kinase receptor family has been shown to have an important role in tumorigenesis, and the expression of its receptor members is frequently deregulated in many types of solid tumors. Various drugs targeting these receptors have been approved for cancer treatment. Particularly, in br...

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Vydáno v:Cell Death Dis
Hlavní autoři: De Cola, A, Volpe, S, Budani, M C, Ferracin, M, Lattanzio, R, Turdo, A, D'Agostino, D, Capone, E, Stassi, G, Todaro, M, Di Ilio, C, Sala, G, Piantelli, M, Negrini, M, Veronese, A, De Laurenzi, V
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650737/
https://ncbi.nlm.nih.gov/pubmed/26181203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.192
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