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Role of acid sphingomyelinase bioactivity in human CD4(+) T-cell activation and immune responses
Acid sphingomyelinase (ASM), a lipid hydrolase enzyme, has the potential to modulate various cellular activation responses via the generation of ceramide and by interaction with cellular receptors. We have hypothesized that ASM modulates CD4(+) T-cell receptor activation and impacts immune responses...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4650726/ https://ncbi.nlm.nih.gov/pubmed/26203857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.178 |
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