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Metabolic stress induces a Wnt-dependent cancer stem cell-like state transition

Reciprocal interactions between cancer cells and the tumor microenvironment drive multiple clinically significant behaviors including dormancy, invasion, and metastasis as well as therapy resistance. These microenvironment-dependent phenotypes share typical characteristics with cancer stem cells (CS...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Lee, E, Yang, J, Ku, M, Kim, N H, Park, Y, Park, C B, Suh, J-S, Park, E S, Yook, J I, Mills, G B, Huh, Y-M, Cheong, J-H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650724/
https://ncbi.nlm.nih.gov/pubmed/26136078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.171
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