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aBETting therapeutic resistance by Wnt signaling

BET inhibition has emerged as a promising epigenetic therapy for malignancies in the last five years, but little consensus has developed regarding what may mediate the axis between sensitivity and resistance. Two recent papers published in Nature attempt to address this question in acute myeloid leu...

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Engelke, Carl G, Chinnaiyan, Arul M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650429/
https://ncbi.nlm.nih.gov/pubmed/26516144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2015.127
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