Retinol dehydrogenase 8 and ATP‐binding cassette transporter 4 modulate dark adaptation of M‐cones in mammalian retina

KEY POINTS: This study explores the molecular mechanisms that regulate the recycling of chromophore required for pigment regeneration in mammalian cones. We report that two chromophore binding proteins, retinol dehydrogenase 8 (RDH8) and photoreceptor‐specific ATP‐binding cassette transporter (ABCA4...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Physiol
Auteurs principaux: Kolesnikov, Alexander V., Maeda, Akiko, Tang, Peter H., Imanishi, Yoshikazu, Palczewski, Krzysztof, Kefalov, Vladimir J.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2015
Sujets:
Neuroscience ‐ Cellular/Molecular
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650407/
https://ncbi.nlm.nih.gov/pubmed/26350353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271285
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