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Fabrication of three-dimensional hydrogel scaffolds for modeling shunt failure by tissue obstruction in hydrocephalus

BACKGROUND: Shunt obstruction in the treatment of hydrocephalus is poorly understood, is multi-factorial, and in many cases is modeled ineffectively. Several mechanisms may be responsible, one of which involves shunt infiltration by reactive cells from the brain parenchyma. This has not been modeled...

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Pubblicato in:Fluids Barriers CNS
Autori principali: Harris, Carolyn, Pearson, Kelsie, Hadley, Kristen, Zhu, Shanshan, Browd, Samuel, Hanak, Brian W., Shain, William
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650346/
https://ncbi.nlm.nih.gov/pubmed/26578355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-015-0023-9
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