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High fat plus high cholesterol diet lead to hepatic steatosis in zebrafish larvae: a novel model for screening anti-hepatic steatosis drugs

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD), characterized as excessive lipid accumulation within hepatocytes, is growing in prevalence. The exploitation of effective drugs for NAFLD has been proven challenging. Herein, we aimed to establish a dietary model of hepatic steatosis using trans...

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Detalhes bibliográficos
Publicado no:Nutr Metab (Lond)
Main Authors: Dai, Wencong, Wang, Kunyuan, Zheng, Xinchun, Chen, Xiaohui, Zhang, Wenqing, Zhang, Yiyue, Hou, Jinlin, Liu, Li
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650307/
https://ncbi.nlm.nih.gov/pubmed/26583037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12986-015-0036-z
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