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Preparation of a conjugation-ready thiol responsive molecular switch

In this work we synthesize molecular switches that are responsive to cysteine, homocysteine, and glutathione; three redox systems that make up the majority of the body’s antioxidant defenses. Synthesized spiropyran isomers with conjugation-ready linkages showed good selectivity of response to these...

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Detalhes bibliográficos
Publicado no:Tetrahedron Lett
Main Authors: Tautges, Brandon, Or, Victor, Garcia, Joel, Shaw, Jared T., Louie, Angelique Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649948/
https://ncbi.nlm.nih.gov/pubmed/26594066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2015.10.019
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