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Preparation of a conjugation-ready thiol responsive molecular switch

In this work we synthesize molecular switches that are responsive to cysteine, homocysteine, and glutathione; three redox systems that make up the majority of the body’s antioxidant defenses. Synthesized spiropyran isomers with conjugation-ready linkages showed good selectivity of response to these...

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Dettagli Bibliografici
Pubblicato in:Tetrahedron Lett
Autori principali: Tautges, Brandon, Or, Victor, Garcia, Joel, Shaw, Jared T., Louie, Angelique Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649948/
https://ncbi.nlm.nih.gov/pubmed/26594066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2015.10.019
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