Alpha-2-macroglobulin loaded microcapsules enhance human leukocyte functions and innate immune response

Synthetic microstructures can be engineered to deliver bioactive compounds impacting on their pharmacokinetics and pharmacodynamics. Herein, we applied dextran-based layer-by-layer (LbL) microcapsules to deliver alpha-2-macroglobulin (α2MG), a protein with modulatory properties in inflammation. Exte...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Canova, Donata Federici, Pavlov, Anton M., Norling, Lucy V., Gobbetti, Thomas, Brunelleschi, Sandra, Le Fauder, Pauline, Cenac, Nicolas, Sukhorukov, Gleb B., Perretti, Mauro
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science Publishers 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649706/
https://ncbi.nlm.nih.gov/pubmed/26385167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.09.021
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