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The AP-3 adaptor complex mediates sorting of yeast and mammalian PQ-loop-family basic amino acid transporters to the vacuolar/lysosomal membrane

The limiting membrane of lysosomes in animal cells and that of the vacuole in yeast include a wide variety of transporters, but little is known about how these proteins reach their destination membrane. The mammalian PQLC2 protein catalyzes efflux of basic amino acids from the lysosome, and the simi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Llinares, Elisa, Barry, Abdoulaye Oury, André, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649669/
https://ncbi.nlm.nih.gov/pubmed/26577948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16665
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