Asymmetric Wnt Pathway Signaling Facilitates Stem Cell-Like Divisions via the Nonreceptor Tyrosine Kinase FRK-1 in Caenorhabditis elegans

Asymmetric cell division is critical during development, as it influences processes such as cell fate specification and cell migration. We have characterized FRK-1, a homolog of the mammalian Fer nonreceptor tyrosine kinase, and found it to be required for differentiation and maintenance of epitheli...

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Publicado en:Genetics
Autores principales: Mila, Danielle, Calderon, Adriana, Baldwin, Austin T., Moore, Kelsey M., Watson, McLane, Phillips, Bryan T., Putzke, Aaron P.
Formato: Artigo
Lenguaje:Inglês
Publicado: Genetics Society of America 2015
Materias:
Investigations
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649634/
https://ncbi.nlm.nih.gov/pubmed/26358719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.181412
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