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High-resolution in-depth imaging of optically cleared thick samples using an adaptive SPIM

Today, Light Sheet Fluorescence Microscopy (LSFM) makes it possible to image fluorescent samples through depths of several hundreds of microns. However, LSFM also suffers from scattering, absorption and optical aberrations. Spatial variations in the refractive index inside the samples cause major ch...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Masson, Aurore, Escande, Paul, Frongia, Céline, Clouvel, Grégory, Ducommun, Bernard, Lorenzo, Corinne
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649629/
https://ncbi.nlm.nih.gov/pubmed/26576666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16898
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