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Peritoneal VEGF-A expression is regulated by TGF-β1 through an ID1 pathway in women with endometriosis

VEGF-A, an angiogenic factor, is increased in the peritoneal fluid of women with endometriosis. The cytokine TGF-β1 is thought to play a role in the establishment of endometriosis lesions. Inhibitor of DNA binding (ID) proteins are transcriptional targets of TGF-β1 and ID1 has been implicated in VEG...

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Udgivet i:Sci Rep
Main Authors: Young, Vicky J., Ahmad, Syed F., Brown, Jeremy K., Duncan, W. Colin, Horne, Andrew W.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649623/
https://ncbi.nlm.nih.gov/pubmed/26577912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16859
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