Bortezomib sensitises TRAIL-resistant HPV-positive head and neck cancer cells to TRAIL through a caspase-dependent, E6-independent mechanism

Human papillomavirus (HPV) is causative for a new and increasing form of head and neck squamous cell carcinomas (HNSCCs). Although localised HPV-positive cancers have a favourable response to radio-chemotherapy (RT/CT), the impact of HPV in advanced or metastatic HNSCC remains to be defined and targ...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Bullenkamp, J, Raulf, N, Ayaz, B, Walczak, H, Kulms, D, Odell, E, Thavaraj, S, Tavassoli, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649534/
https://ncbi.nlm.nih.gov/pubmed/25341043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.455
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