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Atypical PKC-iota Controls Stem Cell Expansion via Regulation of the Notch Pathway

The number of stem/progenitor cells available can profoundly impact tissue homeostasis and the response to injury or disease. Here, we propose that an atypical PKC, Prkci, is a key player in regulating the switch from an expansion to a differentiation/maintenance phase via regulation of Notch, thus...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Mah, In Kyoung, Soloff, Rachel, Hedrick, Stephen M., Mariani, Francesca V.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649379/
https://ncbi.nlm.nih.gov/pubmed/26527382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.09.021
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