Mechanisms of three-dimensional growth of thyroid cells during long-term simulated microgravity

Three-dimensional multicellular spheroids (MCS) of human cells are important in cancer research. We investigated possible mechanisms of MCS formation of thyroid cells. Both, normal Nthy-ori 3–1 thyroid cells and the poorly differentiated follicular thyroid cancer cells FTC-133 formed MCS within 7 an...

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Published in:Sci Rep
Main Authors: Kopp, Sascha, Warnke, Elisabeth, Wehland, Markus, Aleshcheva, Ganna, Magnusson, Nils E., Hemmersbach, Ruth, Juhl Corydon, Thomas, Bauer, Johann, Infanger, Manfred, Grimm, Daniela
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649336/
https://ncbi.nlm.nih.gov/pubmed/26576504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16691
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