Colistin Population Pharmacokinetics after Application of a Loading Dose of 9 MU Colistin Methanesulfonate in Critically Ill Patients

Colistin has been revived, in the era of extensively drug-resistant (XDR) Gram-negative infections, as the last-resort treatment in critically ill patients. Recent studies focusing on the optimal dosing strategy of colistin have demonstrated the necessity of a loading dose at treatment initiation (D...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Karaiskos, Ilias, Friberg, Lena E., Pontikis, Konstantinos, Ioannidis, Konstantinos, Tsagkari, Vasiliki, Galani, Lamprini, Kostakou, Eirini, Baziaka, Fotini, Paskalis, Charalambos, Koutsoukou, Antonia, Giamarellou, Helen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649253/
https://ncbi.nlm.nih.gov/pubmed/26369974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00554-15
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