Toxicity of Amphotericin B Deoxycholate-Based Induction Therapy in Patients with HIV-Associated Cryptococcal Meningitis

Amphotericin B deoxycholate (AmBd) is the recommended induction treatment for HIV-associated cryptococcal meningitis (CM). Its use is hampered by toxicities that include electrolyte abnormalities, nephrotoxicity, and anemia. Protocols to minimize toxicity are applied inconsistently. In a clinical tr...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Bicanic, Tihana, Bottomley, Christian, Loyse, Angela, Brouwer, Annemarie E., Muzoora, Conrad, Taseera, Kabanda, Jackson, Arthur, Phulusa, Jacob, Hosseinipour, Mina C., van der Horst, Charles, Limmathurotsakul, Direk, White, Nicholas J., Wilson, Douglas, Wood, Robin, Meintjes, Graeme, Harrison, Thomas S., Jarvis, Joseph N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649151/
https://ncbi.nlm.nih.gov/pubmed/26349818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01698-15
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