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Motivational Effects of Methylphenidate are Associated with GABRA2 Variants Conferring Addiction Risk

Background: Variations in the GABRA2 gene, encoding α2 subunits of GABA(A) receptors, have been associated with risk for addiction to several drugs, but the mechanisms by which variations in non-coding regions of GABRA2 increase risk for addictions are not understood. Mice with deletion of GABRA2 sh...

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Detalhes bibliográficos
Publicado no:Front Behav Neurosci
Main Authors: Duka, Theodora, Dixon, Claire I., Trick, Leanne, Crombag, Hans S., King, Sarah L., Stephens, David N.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649050/
https://ncbi.nlm.nih.gov/pubmed/26635556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2015.00304
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