PAK1 and CtBP1 Regulate the Coupling of Neuronal Activity to Muscle Chromatin and Gene Expression

Acetylcholine receptor (AChR) expression in innervated muscle is limited to the synaptic region. Neuron-induced electrical activity participates in this compartmentalization by promoting the repression of AChR expression in the extrasynaptic regions. Here, we show that the corepressor CtBP1 (C-termi...

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Publicado en:Mol Cell Biol
Autores principales: Thomas, Jean-Luc, Moncollin, Vincent, Ravel-Chapuis, Aymeric, Valente, Carmen, Corda, Daniela, Méjat, Alexandre, Schaeffer, Laurent
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648822/
https://ncbi.nlm.nih.gov/pubmed/26416879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00354-15
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