P16/INK4A up-regulation mediated by SIX6 defines retinal ganglion cell pathogenesis in glaucoma

Glaucoma, a blinding neurodegenerative disease, whose risk factors include elevated intraocular pressure (IOP), age and genetics, is characterized by accelerated and progressive retinal ganglion cell (RGC) death. Despite decades of research, the mechanism of RGC death in glaucoma is still unknown. H...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell
Asıl Yazarlar: Skowronska-Krawczyk, Dorota, Zhao, Ling, Zhu, Jie, Weinreb, Robert N., Luo, Jing, Flagg, Ken, Patel, Sherrina, Wen, Cindy, Krupa, Martin, Luo, Hongrong, Ouyang, Hong, Lin, Danni, Wang, Wengqiu, Li, Gen, Xu, Yanxin, Cao, Guiqun, Li, Oulan, Chung, Christopher, Yeh, Emily, Jafari, Maryam, Ai, Michael, Zhong, Zheng, Shi, William, Zheng, Lianghong, Krawczyk, Michal, Chen, Daniel, Shi, Catherine, Zin, Carolyn, Zhu, Jin, Mellon, Pamela L., Gao, Weiwei, Zhang, Liangfang, Sun, Xiaodong, Zhong, Sheng, Zhuo, Yehong, Rosenfeld, Michael G., Liu, Yizhi, Zhang, Kang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648709/
https://ncbi.nlm.nih.gov/pubmed/26365380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.07.027
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