P16/INK4A up-regulation mediated by SIX6 defines retinal ganglion cell pathogenesis in glaucoma

Glaucoma, a blinding neurodegenerative disease, whose risk factors include elevated intraocular pressure (IOP), age and genetics, is characterized by accelerated and progressive retinal ganglion cell (RGC) death. Despite decades of research, the mechanism of RGC death in glaucoma is still unknown. H...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell
Egile Nagusiak: Skowronska-Krawczyk, Dorota, Zhao, Ling, Zhu, Jie, Weinreb, Robert N., Luo, Jing, Flagg, Ken, Patel, Sherrina, Wen, Cindy, Krupa, Martin, Luo, Hongrong, Ouyang, Hong, Lin, Danni, Wang, Wengqiu, Li, Gen, Xu, Yanxin, Cao, Guiqun, Li, Oulan, Chung, Christopher, Yeh, Emily, Jafari, Maryam, Ai, Michael, Zhong, Zheng, Shi, William, Zheng, Lianghong, Krawczyk, Michal, Chen, Daniel, Shi, Catherine, Zin, Carolyn, Zhu, Jin, Mellon, Pamela L., Gao, Weiwei, Zhang, Liangfang, Sun, Xiaodong, Zhong, Sheng, Zhuo, Yehong, Rosenfeld, Michael G., Liu, Yizhi, Zhang, Kang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648709/
https://ncbi.nlm.nih.gov/pubmed/26365380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.07.027
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