P16/INK4A up-regulation mediated by SIX6 defines retinal ganglion cell pathogenesis in glaucoma

Glaucoma, a blinding neurodegenerative disease, whose risk factors include elevated intraocular pressure (IOP), age and genetics, is characterized by accelerated and progressive retinal ganglion cell (RGC) death. Despite decades of research, the mechanism of RGC death in glaucoma is still unknown. H...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Mol Cell
Main Authors: Skowronska-Krawczyk, Dorota, Zhao, Ling, Zhu, Jie, Weinreb, Robert N., Luo, Jing, Flagg, Ken, Patel, Sherrina, Wen, Cindy, Krupa, Martin, Luo, Hongrong, Ouyang, Hong, Lin, Danni, Wang, Wengqiu, Li, Gen, Xu, Yanxin, Cao, Guiqun, Li, Oulan, Chung, Christopher, Yeh, Emily, Jafari, Maryam, Ai, Michael, Zhong, Zheng, Shi, William, Zheng, Lianghong, Krawczyk, Michal, Chen, Daniel, Shi, Catherine, Zin, Carolyn, Zhu, Jin, Mellon, Pamela L., Gao, Weiwei, Zhang, Liangfang, Sun, Xiaodong, Zhong, Sheng, Zhuo, Yehong, Rosenfeld, Michael G., Liu, Yizhi, Zhang, Kang
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648709/
https://ncbi.nlm.nih.gov/pubmed/26365380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.07.027
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares