P16/INK4A up-regulation mediated by SIX6 defines retinal ganglion cell pathogenesis in glaucoma

Glaucoma, a blinding neurodegenerative disease, whose risk factors include elevated intraocular pressure (IOP), age and genetics, is characterized by accelerated and progressive retinal ganglion cell (RGC) death. Despite decades of research, the mechanism of RGC death in glaucoma is still unknown. H...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Mol Cell
Κύριοι συγγραφείς: Skowronska-Krawczyk, Dorota, Zhao, Ling, Zhu, Jie, Weinreb, Robert N., Luo, Jing, Flagg, Ken, Patel, Sherrina, Wen, Cindy, Krupa, Martin, Luo, Hongrong, Ouyang, Hong, Lin, Danni, Wang, Wengqiu, Li, Gen, Xu, Yanxin, Cao, Guiqun, Li, Oulan, Chung, Christopher, Yeh, Emily, Jafari, Maryam, Ai, Michael, Zhong, Zheng, Shi, William, Zheng, Lianghong, Krawczyk, Michal, Chen, Daniel, Shi, Catherine, Zin, Carolyn, Zhu, Jin, Mellon, Pamela L., Gao, Weiwei, Zhang, Liangfang, Sun, Xiaodong, Zhong, Sheng, Zhuo, Yehong, Rosenfeld, Michael G., Liu, Yizhi, Zhang, Kang
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2015
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648709/
https://ncbi.nlm.nih.gov/pubmed/26365380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.07.027
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