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Encapsulation of PEGylated low-molecular-weight PEI polyplexes in hyaluronic acid hydrogels reduces aggregation

The effective delivery of DNA locally could increase the applicability of gene therapy in tissue regeneration and therapeutic angiogenesis. One promising approach is through use of porous hydrogel scaffolds that incorporate and deliver DNA in the form of nanoparticles to the affected sites. While we...

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Veröffentlicht in:Acta Biomater
Hauptverfasser: Siegman, Shayne, Truong, Norman F., Segura, Tatiana
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648651/
https://ncbi.nlm.nih.gov/pubmed/26391497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2015.09.020
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