Incidence and clinical significance of ESR1 mutations in heavily pretreated metastatic breast cancer patients

BACKGROUND: ESR1 mutation has recently emerged as one of the important mechanisms involved in endocrine resistance. The incidence and clinical implication of ESR1 mutation has not been well evaluated in heavily pretreated breast cancer patients. METHODS: We conducted a retrospective review of advanc...

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Publicado en:Onco Targets Ther
Main Authors: Niu, Jiaxin, Andres, Grant, Kramer, Kim, Kundranda, Madappa N, Alvarez, Ricardo H, Klimant, Eiko, Parikh, Ankur R, Tan, Bradford, Staren, Edgar D, Markman, Maurie
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2015
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648593/
https://ncbi.nlm.nih.gov/pubmed/26648736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S92443
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