Nonspreading Rift Valley Fever Virus Infection of Human Dendritic Cells Results in Downregulation of CD83 and Full Maturation of Bystander Cells

Vaccines based on nonspreading Rift Valley fever virus (NSR) induce strong humoral and robust cellular immune responses with pronounced Th1 polarisation. The present work was aimed to gain insight into the molecular basis of NSR-mediated immunity. Recent studies have demonstrated that wild-type Rift...

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Pubblicato in:PLoS One
Autori principali: Oreshkova, Nadia, Wichgers Schreur, Paul J., Spel, Lotte, Vloet, Rianka P. M., Moormann, Rob J. M., Boes, Marianne, Kortekaas, Jeroen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648518/
https://ncbi.nlm.nih.gov/pubmed/26575844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142670
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